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Effect of lysE deletion on 5-aminovaleramide production in C. glutamicum. Strains expressing Ptuf davB either episomally in the basic lysine producer LYS-1 (A) or genomically in the advanced producer LYS-12 (B) were compared with their respective lysE-deficient derivatives. The data represent the yields for lysine and 5-AVD and the specific growth rate. Cultivations were performed in a miniaturized <t>bioreactor</t> system with glucose minimal medium. Data represent mean ± standard error from three biological replicates
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Effect of lysE deletion on 5-aminovaleramide production in C. glutamicum. Strains expressing Ptuf davB either episomally in the basic lysine producer LYS-1 (A) or genomically in the advanced producer LYS-12 (B) were compared with their respective lysE-deficient derivatives. The data represent the yields for lysine and 5-AVD and the specific growth rate. Cultivations were performed in a miniaturized <t>bioreactor</t> system with glucose minimal medium. Data represent mean ± standard error from three biological replicates
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Effect of lysE deletion on 5-aminovaleramide production in C. glutamicum. Strains expressing Ptuf davB either episomally in the basic lysine producer LYS-1 (A) or genomically in the advanced producer LYS-12 (B) were compared with their respective lysE-deficient derivatives. The data represent the yields for lysine and 5-AVD and the specific growth rate. Cultivations were performed in a miniaturized <t>bioreactor</t> system with glucose minimal medium. Data represent mean ± standard error from three biological replicates
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Effect of lysE deletion on 5-aminovaleramide production in C. glutamicum. Strains expressing Ptuf davB either episomally in the basic lysine producer LYS-1 (A) or genomically in the advanced producer LYS-12 (B) were compared with their respective lysE-deficient derivatives. The data represent the yields for lysine and 5-AVD and the specific growth rate. Cultivations were performed in a miniaturized bioreactor system with glucose minimal medium. Data represent mean ± standard error from three biological replicates

Journal: Microbial Cell Factories

Article Title: Metabolic engineering of Corynebacterium glutamicum for high-yield de novo biosynthesis of 5-aminovaleramide, a promising bio-based monomer

doi: 10.1186/s12934-026-02922-1

Figure Lengend Snippet: Effect of lysE deletion on 5-aminovaleramide production in C. glutamicum. Strains expressing Ptuf davB either episomally in the basic lysine producer LYS-1 (A) or genomically in the advanced producer LYS-12 (B) were compared with their respective lysE-deficient derivatives. The data represent the yields for lysine and 5-AVD and the specific growth rate. Cultivations were performed in a miniaturized bioreactor system with glucose minimal medium. Data represent mean ± standard error from three biological replicates

Article Snippet: Strains were grown in 1 L lab-scale bioreactors, monitored and controlled using the DASGIP control software (SR0700ODLS, Eppendorf, Hamburg, Germany).

Techniques: Expressing